Solute Carrier Family 22 Member 5

Preferred Label : Solute Carrier Family 22 Member 5;

MeSH definition : A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency.;

MeSH synonym : High-Affinity Carnitine Transporter; Carnitine Transporter, High-Affinity; High Affinity Carnitine Transporter; Transporter, High-Affinity Carnitine; OCTN2 Protein; Sodium-Dependent Carnitine Cotransporter; Carnitine Cotransporter, Sodium-Dependent; Sodium Dependent Carnitine Cotransporter; Organic Cation-Carnitine Transporter 2; Organic Cation Carnitine Transporter 2; SLC22A5 Protein;

Details

Origin ID

D000074058;

UMLS CUI

C4319821;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Solute Carrier Family 22 Member 5 [MeSH concept]
Related MeSH Supplementary Concept(s)
- SLC22A5 protein, human [MeSH Supplementary Concept]
- Slc22a5 protein, mouse [MeSH Supplementary Concept]
- Slc22a5 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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