T-Cell Intracellular Antigen-1

Preferred Label : T-Cell Intracellular Antigen-1;

MeSH definition : An RNA-binding protein characterized by three RNA RECOGNITION MOTIFS. It binds to AU RICH ELEMENTS in the 3'-untranslated regions of mRNA and regulates alternative pre-RNA splicing and mRNA translation; it may also function in APOPTOSIS. Mutations in the TIA-1 gene are associated with WELANDER DISTAL MYOPATHY.;

MeSH synonym : Intracellular Antigen-1, T-Cell; T Cell Intracellular Antigen 1; T-Cell-Restricted Intracellular Antigen-1; Intracellular Antigen-1, T-Cell-Restricted; T Cell Restricted Intracellular Antigen 1; RNA-Binding Protein TIA-1; RNA Binding Protein TIA 1; TIA-1, RNA-Binding Protein;

Details

Origin ID

D000074019;

UMLS CUI

C4318625;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Nucleolysin TIA-1 Isoform p40 [NCIt concept]
- TIA1 cytotoxic granule associated RNA binding protein [ORDO Gene]
- TIA1 cytotoxic granule associated RNA binding protein [HGNC gene]
Record concept(s)
- T-Cell Intracellular Antigen-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TIA1 protein, human [MeSH Supplementary Concept]
- Tia1 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients