Dishevelled Proteins

Preferred Label : Dishevelled Proteins;

MeSH definition : A family of proteins that are key components of the WNT SIGNALING PATHWAY, where they function downstream of FRIZZLED RECEPTORS. They contain an N-terminal dishevelled-AXIN PROTEIN (DIX) domain, which mediates oligomerization; a central PDZ DOMAIN which binds to the frizzled receptor; and a C-terminal DEP domain which facilitates binding to the CELL MEMBRANE. Dishevelled proteins have important functions in CELL DIFFERENTIATION and establishing CELL POLARITY.;

MeSH synonym : Dishevelled Protein;

DeCS synonym : Dishevelled-1 Protein; Dishevelled-2 Protein; Dishevelled-3 Protein;

MeSH hyponym : Dishevelled 3 Protein; Dishevelled 1 Protein; Dishevelled 2 Protein;

Détails

Origin ID

D000072261;

UMLS CUI

C0251074;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Dishevelled-1 Protein [MeSH concept]
- Dishevelled-2 Protein [MeSH concept]
- Dishevelled-3 Protein [MeSH concept]
- dishevelled proteins [MeSH concept]
Related MeSH Supplementary Concept(s)
- DSH-1 protein, C elegans [MeSH Supplementary Concept]
- DVL1 protein, Xenopus [MeSH Supplementary Concept]
- DVL1 protein, human [MeSH Supplementary Concept]
- DVL2 protein, human [MeSH Supplementary Concept]
- DVL3 protein, human [MeSH Supplementary Concept]
- Dvl1 protein, mouse [MeSH Supplementary Concept]
- Dvl1 protein, rat [MeSH Supplementary Concept]
- Dvl2 protein, Xenopus [MeSH Supplementary Concept]
- Dvl2 protein, mouse [MeSH Supplementary Concept]
- Dvl3 protein, mouse [MeSH Supplementary Concept]
- Dvl3 protein, rat [MeSH Supplementary Concept]
- dsh protein, Drosophila [MeSH Supplementary Concept]
- dsh-2 protein, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Position du mot-clé dans l'(les) arborescence(s) :

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