ERG1 Potassium Channel

Preferred Label : ERG1 Potassium Channel;

MeSH definition : One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.;

MeSH synonym : Channel, ERG1 Potassium; Potassium Channel, ERG1; Potassium Voltage-Gated Channel, Subfamily H, Member 2; Ether-A-Go-Go-Related Potassium Channel 1; Ether A Go Go Related Potassium Channel 1;

DeCS synonym : Kv11.1 Protein-Potassium Channel;

MeSH hyponym : Channel, Kv11.1 Protein-Potassium; Kv11.1 Protein Potassium Channel; Protein-Potassium Channel, Kv11.1;

Details

Origin ID

D000072237;

UMLS CUI

C0965997;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Potassium channel, voltage-gated, subfamily h, member 2 [OMIM gene]
- potassium voltage-gated channel subfamily H member 2 [ORDO Gene]
- potassium voltage-gated channel subfamily H member 2 [HGNC gene]
Record concept(s)
- ERG1 potassium channel [MeSH concept]
- Kv11.1 Protein-Potassium Channel [MeSH concept]
Related MeSH Supplementary Concept(s)
- ERG1 A protein, mouse [MeSH Supplementary Concept]
- ERG1 B protein, mouse [MeSH Supplementary Concept]
- KCNH2 protein, human [MeSH Supplementary Concept]
- Kcnh2 protein, mouse [MeSH Supplementary Concept]
- Kcnh2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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