ADAM12 Protein

Preferred Label : ADAM12 Protein;

MeSH definition : A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS.;

MeSH synonym : ADAM-12 Protein; Meltrin-alpha Protein; Meltrin alpha Protein; Disintegrin and Metalloproteinase Domain-Containing Protein 12; Disintegrin and Metalloproteinase Domain Containing Protein 12; ADAM 12 Protein;

DeCS synonym : ADAM12-L Protein; ADAM12-S Protein;

MeSH hyponym : ADAM12 S Protein; ADAM12 L Protein;

MeSH Related Number : EC 3.4.24.82;

Registry Number MeSH : EC 3.4.24.-;

Details

Origin ID

D000072199;

UMLS CUI

C0535503;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Disintegrin and Metalloproteinase Domain-Containing Protein 12 [NCIt concept]
Record concept(s)
- ADAM12 Protein [MeSH concept]
- ADAM12-L Protein [MeSH concept]
- ADAM12-S Protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- ADAM12 protein, human [MeSH Supplementary Concept]
- Adam12 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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