Patched-2 Receptor

Preferred Label : Patched-2 Receptor;

MeSH definition : A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.;

MeSH synonym : Patched 2 Receptor; Receptor, Patched-2; PTCH2 Protein; Patched Receptor-2; Patched Receptor 2; Patched-2 Protein; Patched 2 Protein; Patched Homolog-2; Patched Homolog 2;

Details

Origin ID

D000072082;

UMLS CUI

C4255234;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Protein Patched Homolog 2 [NCIt concept]
Record concept(s)
- Patched-2 Receptor [MeSH concept]
Related MeSH Supplementary Concept(s)
- PTCH2 protein, human [MeSH Supplementary Concept]
- Ptch2 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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