MeSH definition : A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED
RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations
in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL
CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of
the URINARY BLADDER.;
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED
RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations
in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL
CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of
the URINARY BLADDER.
Allowable qualifiers