" /> Transcription Factor HES-1 - CISMeF





Preferred Label : Transcription Factor HES-1;

MeSH definition : A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.;

MeSH synonym : HES-1, Transcription Factor; Transcription Factor HES 1; Hairy-Like Transcription Factor; Hairy Like Transcription Factor; Transcription Factor, Hairy-Like; Hairy and Enhancer of Split 1 Protein;

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A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.

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27/07/2025


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