Fibrillin-1 - CISMeF

Preferred Label : Fibrillin-1;

MeSH definition : A fibrillin (FBN1) that functions as a structural support protein for MICROFIBRILS. It also regulates the maturation of OSTEOBLASTS by controlling the availability and concentration of TGF-BETA and BONE MORPHOGENETIC PROTEINS. Mutations in the FBN1 gene are associated with MARFAN SYNDROME.;

MeSH synonym : Fibrillin 1;

DeCS synonym : Profibrillin 1;

MeSH hyponym : Profibrillin-1;

Wikipedia link : https://en.wikipedia.org/wiki/Fibrillin-1;

Details

Origin ID

D000071838;

UMLS CUI

C0244756;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Fibrillin 1 [OMIM gene]
- Fibrillin-1 [NCIt concept]
- fibrillin 1 [ORDO Gene]
- fibrillin 1 [HGNC gene]
Record concept(s)
- fibrillin-1 [MeSH concept]
- profibrillin 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- FBN1 protein, human [MeSH Supplementary Concept]
- Fbn1 protein, mouse [MeSH Supplementary Concept]
- Fbn1 protein, rat [MeSH Supplementary Concept]
- asprosin peptide, rat [MeSH Supplementary Concept]
- asprosin protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Fibrillin-1 [NCIt concept]
- Fibrillin-1 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients