MeSH definition : A family of extracellular matrix glycoproteins that is structurally similar to LATENT
TGF-BETA BINDING PROTEINS, but contain additional TGF-beta binding domains, in addition
to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm MICROFIBRILS
that function in a variety of cell interactions with the EXTRACELLULAR MATRIX and
developmental processes such as ELASTIC TISSUE maintenance and assembly, and the targeting
of growth factors to the extracellular matrix.;
A family of extracellular matrix glycoproteins that is structurally similar to LATENT
TGF-BETA BINDING PROTEINS, but contain additional TGF-beta binding domains, in addition
to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm MICROFIBRILS
that function in a variety of cell interactions with the EXTRACELLULAR MATRIX and
developmental processes such as ELASTIC TISSUE maintenance and assembly, and the targeting
of growth factors to the extracellular matrix.