Wnt-5a Protein

Preferred Label : Wnt-5a Protein;

MeSH definition : A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells.;

MeSH synonym : Wnt 5a Protein; Wingless-Type MMTV Integration Site Family, Member 5A; Wingless Type MMTV Integration Site Family, Member 5A; Wnt5a Protein;

Details

Origin ID

D000071818;

UMLS CUI

C4255015;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Protein Wnt-5a [NCIt concept]
- Wingless-type mmtv integration site family, member 5a [OMIM gene]
- Wnt family member 5A [ORDO Gene]
- Wnt family member 5A [HGNC gene]
Record concept(s)
- Wnt-5a Protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- WNT5A protein, human [MeSH Supplementary Concept]
- Wnt-5A protein, ambystoma mexicanum [MeSH Supplementary Concept]
- Wnt5a protein, Xenopus [MeSH Supplementary Concept]
- Wnt5a protein, mouse [MeSH Supplementary Concept]
- Wnt5a protein, rat [MeSH Supplementary Concept]
- Wnt5a protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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