Tartrate-Resistant Acid Phosphatase

Preferred Label : Tartrate-Resistant Acid Phosphatase;

MeSH definition : One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.;

MeSH synonym : Acid Phosphatase, Tartrate-Resistant; Phosphatase, Tartrate-Resistant Acid; Tartrate Resistant Acid Phosphatase; TRAcP;

DeCS synonym : TRAP Type 5 AcPase; Uteroferrin;

MeSH hyponym : Acid Phosphatase V; Phosphatase V, Acid; V, Acid Phosphatase; AcPase V; V, AcPase; Type 5 Acid Phosphatase; Tartrate-Resistant Acid Phosphatase Type 5; Tartrate Resistant Acid Phosphatase Type 5;

Registry Number MeSH : EC 3.1.3.2;

Wikipedia link : https://en.wikipedia.org/wiki/Tartrate-resistant acid phosphatase;

UNII : EC 3.1.3.2;

Details

Origin ID

D000071681;

UMLS CUI

C0297331;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Acid phosphatase bone isoenzyme (substance) [SNOMED CT concept]
- Acid phosphatase tartrate resistant [LOINC component]
- Phosphatase, acid, type 5, tartrate-resistant [OMIM gene]
- Tartrate-Resistant Acid Phosphatase Type 5 [NCIt concept]
- Tartrate-resistant acid phosphatase [MedDRA Preferred Term]
- Tartrate-resistant acid phosphatase stain [LOINC method]
- acid phosphatase 5, tartrate resistant [ORDO Gene]
- acid phosphatase 5, tartrate resistant [HGNC gene]
- acid phosphatase tartrate resistant [medical devices type]
Record concept(s)
- TRAP Type 5 AcPase [MeSH concept]
- Uteroferrin [MeSH concept]
- tartrate-resistant acid phosphatase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ACP5 protein, human [MeSH Supplementary Concept]
- Acp5 protein, mouse [MeSH Supplementary Concept]
- Acp5 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Acid phosphatase bone isoenzyme (substance) [SNOMED CT concept]
- Acid phosphatase tartrate resistant [LOINC component]

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