" /> Werner Syndrome Helicase - CISMeF





Preferred Label : Werner Syndrome Helicase;

MeSH definition : A DNA-dependent helicase and 3'-5' exonuclease. It has 3'- 5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS. Mutations in the WRN gene are associated with WERNER SYNDROME.;

MeSH synonym : Helicase, Werner Syndrome; Werner Syndrome ATP-Dependent Helicase; Werner Syndrome ATP Dependent Helicase; RECQL2 Protein; Werner Syndrome RecQ-Like Helicase; Werner Syndrome RecQ Like Helicase; RECQ3 Protein;

Registry Number MeSH : EC 3.6.4.12;

Wikipedia link : https://en.wikipedia.org/wiki/Werner syndrome helicase;

UNII : EC 3.6.4.12;

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A DNA-dependent helicase and 3'-5' exonuclease. It has 3'- 5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS. Mutations in the WRN gene are associated with WERNER SYNDROME.

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27/07/2025


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