Autophagy-Related Protein 5

Preferred Label : Autophagy-Related Protein 5;

MeSH definition : An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.;

MeSH synonym : Autophagy Related Protein 5; Apoptosis-Specific Protein; Apoptosis Specific Protein; ATG5 Protein; ATG-5 Protein; ATG 5 Protein; Autophagy Protein-5; Autophagy Protein 5; Autophagy-Related 5 Protein; Autophagy Related 5 Protein;

Details

Origin ID

D000071187;

UMLS CUI

C4255186;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Autophagy Protein 5 [NCIt concept]
- Autophagy-related 5 [OMIM gene]
Record concept(s)
- Autophagy-Related Protein 5 [MeSH concept]
Related MeSH Supplementary Concept(s)
- ATG5 protein, S cerevisiae [MeSH Supplementary Concept]
- ATG5 protein, human [MeSH Supplementary Concept]
- Atg5 protein, arabidopsis [MeSH Supplementary Concept]
- Atg5 protein, mouse [MeSH Supplementary Concept]
- Atg5 protein, rat [MeSH Supplementary Concept]
- Atg5 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

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