Beclin-1 - CISMeF

Preferred Label : Beclin-1;

MeSH definition : An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.;

MeSH synonym : Beclin 1; Beclin-1 Protein; Beclin 1 Protein; GT197 Protein; ATG-6 Protein; ATG 6 Protein; Coiled-coil Myosin-like Bcl2-interacting Protein; Coiled coil Myosin like Bcl2 interacting Protein; Beclin1; ATG6 Protein;

Details

Origin ID

D000071186;

UMLS CUI

C4255099;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- BECN1 wt Allele [NCIt concept]
- Beclin 1 [OMIM gene]
- Beclin-1 [NCIt concept]
- beclin 1 [HGNC gene]
Record concept(s)
- Beclin-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- Atg6 protein, drosophila [MeSH Supplementary Concept]
- BECN1 protein, human [MeSH Supplementary Concept]
- Becn1 protein, mouse [MeSH Supplementary Concept]
- Becn1 protein, rat [MeSH Supplementary Concept]
- Becn1 protein, zebrafish [MeSH Supplementary Concept]
- beclin 1 protein, S cerevisiae [MeSH Supplementary Concept]
- beclin 1 protein, arabidopsis [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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