Signaling Lymphocytic Activation Molecule Family

Preferred Label : Signaling Lymphocytic Activation Molecule Family;

MeSH definition : Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation.;

MeSH synonym : SLAM Family Receptors; Signaling Lymphocytic Activation Molecule Receptors; Signaling Lymphocytic Activation Molecule Family Receptors; Signaling Lymphocytic Activation Molecules; SLAMF Receptors;

Details

Origin ID

D000071176;

UMLS CUI

C4277631;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Signaling Lymphocytic Activation Molecule [NCIt concept]
- Slam family, member 1 [OMIM gene]
Record concept(s)
- Signaling Lymphocytic Activation Molecule Family [MeSH concept]
Related MeSH Supplementary Concept(s)
- CD244 protein, human [MeSH Supplementary Concept]
- CD84 protein, human [MeSH Supplementary Concept]
- Cd244 protein, rat [MeSH Supplementary Concept]
- Cd244a protein, mouse [MeSH Supplementary Concept]
- Cd84 protein, mouse [MeSH Supplementary Concept]
- LY9 protein, human [MeSH Supplementary Concept]
- Ly9 protein, mouse [MeSH Supplementary Concept]
- SLAMF6 protein, human [MeSH Supplementary Concept]
- SLAMF7 protein, human [MeSH Supplementary Concept]
- SLAMF8 protein, human [MeSH Supplementary Concept]
- SLAMF9 protein, human [MeSH Supplementary Concept]
- Slamf6 protein, mouse [MeSH Supplementary Concept]
- Slamf7 protein, mouse [MeSH Supplementary Concept]
- Slamf9 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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