Preferred Label : Trefoil Factors;
MeSH definition : A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS
in vertebrates. Their structure is highly conserved and is defined by a three-leaved
(trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the
trefoil structure through disulfide bridges. Trefoil peptides may form dimers with
each other, or associate with MUCINS and other factors. They are important for maintaining
epithelial integrity and for protection from noxious agents.;
MeSH synonym : Trefoil Factor Family Proteins; Trefoil Proteins; Trefoil Factor Family Peptides; Trefoil Peptides; TFF Peptides; Trefoil Peptide; Peptide, Trefoil; TFF Peptide; Peptide, TFF; Trefoil Factor; Factor, Trefoil; Trefoil Protein; Protein, Trefoil;
Origin ID : D000071162;
UMLS CUI : C0146550;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
A family of small peptides expressed primarily by MUCOUS MEMBRANE EPITHELIAL CELLS
in vertebrates. Their structure is highly conserved and is defined by a three-leaved
(trefoil) domain of 42 or 43 amino acids; it includes six cysteines that create the
trefoil structure through disulfide bridges. Trefoil peptides may form dimers with
each other, or associate with MUCINS and other factors. They are important for maintaining
epithelial integrity and for protection from noxious agents.
