Poly (ADP-Ribose) Polymerase-1

Preferred Label : Poly (ADP-Ribose) Polymerase-1;

MeSH definition : A poly(ADP-ribose) polymerase that contains two ZINC FINGERS in its N-terminal DNA-binding region. It modifies NUCLEAR PROTEINS involved in chromatin architecture and BASE EXCISION REPAIR with POLY ADENOSINE DIPHOSPHATE RIBOSE.;

MeSH synonym : Poly (ADP-Ribose) Synthase-1; PARP1 Protein; PARP-1 Protein; PARP 1 Protein; NAD ADP-ribosyltransferase-1; NAD ADP ribosyltransferase 1;

Registry Number MeSH : EC 2.4.2.30;

UNII : EC 2.4.2.30;

Details

Origin ID

D000071137;

UMLS CUI

C4082864;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
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- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Poly [ADP-Ribose] Polymerase 1 [NCIt concept]
Record concept(s)
- Poly (ADP-Ribose) Polymerase-1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- AT2G31320 protein, Arabidopsis [MeSH Supplementary Concept]
- PARP1 protein, human [MeSH Supplementary Concept]
- Parp protein, Drosophila [MeSH Supplementary Concept]
- Parp1 protein, mouse [MeSH Supplementary Concept]
- Parp1 protein, rat [MeSH Supplementary Concept]
- Parp1 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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