MeSH definition : A protein that is highly expressed in the nervous system as well as other tissues;
its size and structure vary due to polymorphisms. Expanded CAG TRINUCLEOTIDE REPEATS
have been identified in the Huntingtin (HD) Gene of patients with HUNTINGTON DISEASE
and are associated with abnormal PROTEIN AGGREGATES. Huntingtin interacts with proteins
involved in a variety of gene expression and cellular processes; it is also essential
for embryonic development.;
A protein that is highly expressed in the nervous system as well as other tissues;
its size and structure vary due to polymorphisms. Expanded CAG TRINUCLEOTIDE REPEATS
have been identified in the Huntingtin (HD) Gene of patients with HUNTINGTON DISEASE
and are associated with abnormal PROTEIN AGGREGATES. Huntingtin interacts with proteins
involved in a variety of gene expression and cellular processes; it is also essential
for embryonic development.