Tensins - CISMeF

Preferred Label : Tensins;

MeSH definition : A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.;

MeSH synonym : Tensin;

Details

Origin ID

D000070876;

UMLS CUI

C0168424;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Tensin 1 [OMIM gene]
Record concept(s)
- tensins [MeSH concept]
Related MeSH Supplementary Concept(s)
- TNS1 protein, human [MeSH Supplementary Concept]
- TNS2 protein, human [MeSH Supplementary Concept]
- TNS3 protein, human [MeSH Supplementary Concept]
- TNS4 protein, human [MeSH Supplementary Concept]
- Tns1 protein, mouse [MeSH Supplementary Concept]
- Tns1 protein, rat [MeSH Supplementary Concept]
- Tns2 protein, mouse [MeSH Supplementary Concept]
- Tns2 protein, rat [MeSH Supplementary Concept]
- Tns3 protein, mouse [MeSH Supplementary Concept]
- Tns3 protein, rat [MeSH Supplementary Concept]
- Tns4 protein, mouse [MeSH Supplementary Concept]
- Tns4 protein, rat [MeSH Supplementary Concept]
- tns-1 protein, C elegans [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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