" /> Discoidin Domain Receptors - CISMeF





Preferred Label : Discoidin Domain Receptors;

MeSH definition : Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.;

MeSH synonym : Receptors, Discoidin Domain; DDR Proteins; Proteins, DDR; Discoidin Domain Receptor; Receptor, Discoidin Domain;

Registry Number MeSH : EC 2.7.10.1;

UNII : EC 2.7.10.1;

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Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX.

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09/05/2025


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