Preferred Label : Nogo Receptors;
MeSH definition : GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini
that are connected to the GPI by a stalk region rich in prolines, serines and threonines.
They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED
GLYCOPROTEIN and other cell surface glycoproteins. Interactions between nogo receptors
and their ligands modulate nerve growth and NEURONAL PLASTICITY.; GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini
that are connected to the GPI by a stalk region rich in prolines, serines and threonines.
They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED
GLYCOPROTEIN and other cell surface glycoproteins. Interactions between Nogo receptors
and their ligands modulate nerve growth and NEURONAL PLASTICITY.;
MeSH synonym : Receptors, Nogo; Nogo Receptor; Receptor, Nogo;
Origin ID : D000070156;
UMLS CUI : C4255053;
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Automatic exact mappings (from CISMeF team)
Record concept(s)
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Semantic type(s)
GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini
that are connected to the GPI by a stalk region rich in prolines, serines and threonines.
They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED
GLYCOPROTEIN and other cell surface glycoproteins. Interactions between nogo receptors
and their ligands modulate nerve growth and NEURONAL PLASTICITY.
GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini
that are connected to the GPI by a stalk region rich in prolines, serines and threonines.
They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED
GLYCOPROTEIN and other cell surface glycoproteins. Interactions between Nogo receptors
and their ligands modulate nerve growth and NEURONAL PLASTICITY.