Ataxin-2 - CISMeF

Preferred Label : Ataxin-2;

MeSH definition : A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.;

MeSH synonym : Ataxin 2; Ataxin-2 Protein; Ataxin 2 Protein; Protein, Ataxin-2; Spinocerebellar Ataxia Type 2 Protein; ATXN2 Protein; Protein, ATXN2; Atx-2 Protein; Atx 2 Protein; Protein, Atx-2; SCA2 Protein; Protein, SCA2;

Wikipedia link : https://en.wikipedia.org/wiki/Ataxin-2;

Details

Origin ID

D000067698;

UMLS CUI

C0968256;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ATXN2 Gene [NCIt concept]
- Ataxin 2 [OMIM gene]
- Ataxin-2 [NCIt concept]
- ataxin 2 [HGNC gene]
Currated CISMeF NLP mapping
- ataxin 2 [ORDO Gene]
Record concept(s)
- Ataxin-2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- ATX2 protein, Drosophila [MeSH Supplementary Concept]
- ATXN2 protein, human [MeSH Supplementary Concept]
- Atxn2 protein, mouse [MeSH Supplementary Concept]
- Atxn2 protein, rat [MeSH Supplementary Concept]
See also
- spinocerebellar ataxias [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ataxin 2 [ORDO Gene]

Keyword's position in hierarchy(ies) :

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