Myelopathy, htlv-1-associated

Preferred Label : Myelopathy, htlv-1-associated;

Symbol : HAM;

CISMeF acronym : HAM;

Type : Other, mainly phenotypes with suspected mendelian basis;

Alternative titles and symbols : Familial spastic paraparesis, htlv-1-associated;

Description : A tropical spastic paraparesis associated with antibody titers to human T-lymphotropic virus type 1 in the serum was described in Martinique (Gessain et al., 1985) and in Jamaica and Colombia (Rodgers-Johnson et al., 1985); a similar disorder, termed HTLV-1-associated myelopathy, has been found in parts of southwestern Japan, where adult T-cell leukemia/lymphoma (ATLL) is endemic. Osame et al. (1986) first suggested the entity of HTLV-1-associated myelopathy. Miyai et al. (1987) described 2 families with multiple cases of HTLV-1-associated myelopathy. Even though ATLL and HAM were observed in the same area of Japan, there were no observations of the disorders in the same family. It is not known whether the virus that causes ATLL is the same as that associated with HAM, although they seem to be morphologically and immunologically similar. It is possible that they are identical and that;

Inheritance : Possible genetic factors;

Prefixed ID : 159580;

Details

Origin ID

159580;

UMLS CUI

C0030481;

Automatic exact mappings (from CISMeF team)
- Activating Transcription Factor 7-Interacting Protein 1 [NCIt concept]
- Ham [LOINC component]
- Hammer, device (physical object) [SNOMED CT concept]
Currated CISMeF NLP mapping
- HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis [NCIt concept]
- Tropical spastic paraparesis [MedDRA LLT]
- Tropical spastic paraparesis [ORDO Disease]
- Tropical spastic paraparesis [HPO term]
- Tropical spastic paraplegia [ICD-10 Sub-category]
- Tropical spastic paresis [MedDRA Preferred Term]
- htlv 1 associated myelopathy [Disease (Nov.)]
- paraparesis, tropical spastic [MeSH concept]
- paraparesis, tropical spastic [MeSH Descriptor]
DO Cross reference
- tropical spastic paraparesis [DO Concept]
False automatic mappings
- Altretamine/Doxorubicin/Melphalan [NCIt concept]
- Human T-cell lymphotropic virus 1-associated myelopathy-tropical spastic paraparesis (disorder) [Inactive SNOMED CT concept]
HPO term(s)
- Abnormal pyramidal sign [HPO term]
- Myelopathy [HPO term]
- Spastic paraparesis [HPO term]
- Tropical spastic paraparesis [HPO term]
ORDO concept(s)
- Tropical spastic paraparesis [ORDO Disease]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis [NCIt concept]
- HTLV-I-associated myelopathy [MedDRA LLT]
- Human T-cell leukaemia virus type I myelopathy [MedDRA LLT]
- Human T-cell leukemia virus type I myelopathy [MedDRA LLT]
- Human T-cell lymphotropic virus 1-associated myelopathy-tropical spastic paraparesis (disorder) [Inactive SNOMED CT concept]
- Human T-cell lymphotropic virus-associated myelopathy [ICD-11 Sub-sub category]
- Myelopathy caused by Human T-lymphotropic virus 1 (disorder) [SNOMED CT concept]
- Tropical spastic paraparesis [MedDRA LLT]
- Tropical spastic paraparesis [HPO term]
- Tropical spastic paraparesis [ORDO Disease]
- Tropical spastic paraplegia [ICD-10 Sub-category]
- Tropical spastic paresis [MedDRA Preferred Term]
- htlv 1 associated myelopathy [Disease (Nov.)]
- jamaican neuropathy [SNOMED Notion]
- paraparesis, tropical spastic [MeSH Descriptor]
- paraparesis, tropical spastic [MeSH concept]
- tropical spastic paraparesis [DO Concept]

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