Preferred Label : regioselectivity (regioselective);
IUPAC definition : A regioselective reaction is one in which one direction of bond making or breaking
occurs preferentially over all other possible directions. Reactions are termed completely
(100%) regioselective if the discrimination is complete, or partially ( i x /i %),
if the product of reaction at one site predominates over the product of reaction at
other sites. The discrimination may also semi-quantitatively be referred to as high
or low regioselectivity. (Originally the term was restricted to addition reactions
of unsymmetrical reagents to unsymmetrical alkenes.) In the past, the term 'regiospecificity'
was proposed for 100% regioselectivity. This terminology is not recommended owing
to inconsistency with the terms stereoselectivity and stereospecificity.;
Origin ID : R05243;
See also
A regioselective reaction is one in which one direction of bond making or breaking
occurs preferentially over all other possible directions. Reactions are termed completely
(100%) regioselective if the discrimination is complete, or partially ( i x /i %),
if the product of reaction at one site predominates over the product of reaction at
other sites. The discrimination may also semi-quantitatively be referred to as high
or low regioselectivity. (Originally the term was restricted to addition reactions
of unsymmetrical reagents to unsymmetrical alkenes.) In the past, the term 'regiospecificity'
was proposed for 100% regioselectivity. This terminology is not recommended owing
to inconsistency with the terms stereoselectivity and stereospecificity.
