Preferred Label : chemoselectivity (chemoselective);
IUPAC definition : Chemoselectivity is the preferential reaction of a chemical reagent with one of two
or more different functional groups. A reagent has a high chemoselectivity if reaction
occurs with only a limited number of different functional groups. For example, sodium
tetrahydroborate is a more chemoselective reducing agent than is lithium tetrahydroaluminate.
The concept has not been defined in more quantitative terms. The term is also applied
to reacting molecules or intermediates which exhibit selectivity towards chemically
different reagents. Some authors use the term chemospecificity for 100% chemoselectivity.
However, this usage is discouraged.;
Origin ID : C01051;
See also
Chemoselectivity is the preferential reaction of a chemical reagent with one of two
or more different functional groups. A reagent has a high chemoselectivity if reaction
occurs with only a limited number of different functional groups. For example, sodium
tetrahydroborate is a more chemoselective reducing agent than is lithium tetrahydroaluminate.
The concept has not been defined in more quantitative terms. The term is also applied
to reacting molecules or intermediates which exhibit selectivity towards chemically
different reagents. Some authors use the term chemospecificity for 100% chemoselectivity.
However, this usage is discouraged.
