" /> Gastrointestinal stromal tumour, primary site - CISMeF





ICD-11 code : 2B5B;

Preferred Label : Gastrointestinal stromal tumour, primary site;

ICD-11 definition : This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA- activating mutations. It is most frequent in the stomach and to a lesser degree in the small intestine. The prognosis depends on the tumor size and the mitotic activity.;

ICD-11 synonym : gastrointestinal stromal tumour; GIST - [gastrointestinal stromal tumour];

ICD-11 acronym : GIST;

ICD-11 "other" category code : 2B5B.Y;

ICD-11 "unspecified" category code : 2B5B.Z;

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This is the most common mesenchymal tumour that arises in the gastrointestinal tract. It is generally immunohistochemically positive for CD117 (KIT), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA- activating mutations. It is most frequent in the stomach and to a lesser degree in the small intestine. The prognosis depends on the tumor size and the mitotic activity.

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29/07/2025


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