Preferred Label : interleukin 4;
Definition : The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive
helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently
produce additional IL-4 in a positive feedback loop. The cell that initially produces
IL-4, thus inducing Th2 differentiation, has not been identified, but recent studies
suggest that basophils may be the effector cell. (Wikipedia);
Synonyme : IL-4;
Origin ID : ZDQPT18H-0;
Automatic exact mappings (from CISMeF team)
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive
helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently
produce additional IL-4 in a positive feedback loop. The cell that initially produces
IL-4, thus inducing Th2 differentiation, has not been identified, but recent studies
suggest that basophils may be the effector cell. (Wikipedia)
