Vaccine-related autoimmune hepatitis: the same disease as idiopathic autoimmune hepatitis? Two clinical reports and review

Publié le 18 octobre 2017 • Catégorie(s) : Vaccination • Mot(s) clef(s) : hépatite A

Auteur    Marline A. J. van Gemeren
Auteur    Peter van Wijngaarden
Auteur    Michael Doukas
Auteur    Robert A. de Man
Volume    52
Numéro    1
Pages    18-22
Publication    Scandinavian Journal of Gastroenterology
ISSN    1502-7708
Date    Jan 2017
Résumé    Autoimmune hepatitis (AIH) develops in genetically predisposed individuals after an inciting or environmental trigger. These factors are unknown but may include viral infections, environmental toxins, drugs and vaccinations. Few reports are written about vaccination as potential trigger of autoimmune hepatitis. In this article, we additionally describe two vaccine-related cases of AIH. In both cases, long-term immune-suppressive therapy is demanded. Moreover, we present the cases of vaccine-related AIH from literature and compare these with idiopathic AIH and our own cases.