Association of arginase I or nitric oxide-related factors with job strain in healthy workers
Auteur Keiki Ogino
Auteur Tatsuo Ito
Auteur Eri Eguchi
Auteur Kenjiro Nagaoka
Volume 12
Numéro 4
Pages e0175696
Publication PloS One
ISSN 1932-6203
Date 2017
Résumé This study evaluated the associations between job strain and arginase I in 378 healthy Japanese factory workers by a cross-sectional study measuring nitric oxide (NO)-related parameters (arginase I, L-arginine, exhaled nitric oxide (FeNO), and NOx), clinical parameters, and job strain using a Japanese version of the Job Content Questionnaire by Karasek. Arginase I and FEV1% were negatively correlated with job strain and positively correlated with job control and social support. FeNO and hs-CRP were negatively correlated with job strain. Multiple regression analysis showed negative association of arginase I with job strain and positive association with job control and social support in females. It is concluded that serum levels of arginase I may be useful biomarkers for the diagnosis of job stress in healthy female workers, although many factors can be influencing the data.
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doi:10.1371/journal.pone.0175696
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