Veille documentaire MTPH

Médecine du travail du personnel hospitalier

Fatal Encephalopathy Associated with Influenza in a Health Care Professional

Auteur       Kiyoshi Kitano
Auteur       Kiyoshi Furuta
Auteur       Shinichiro Kanai
Auteur       Yo-Ichi Takei
Volume       55
Numéro       5
Pages       533-536
Publication       Internal Medicine (Tokyo, Japan)
ISSN       1349-7235
Date       2016
Résumé       A 41-year-old nurse was referred to our hospital with a fever and disturbed consciousness. She tested positive for influenza antigen. CT and MRI findings revealed low density and intensity areas in the right occipital and lateral lobes with remarkable brain edema, which led to a diagnosis of influenza encephalopathy. Influenza A antibodies in the serum were below the detection limit despite the patient receiving previous vaccination three months earlier. A PCR analysis revealed that the influenza HA gene was classified into clade 3C.2a, subclass AH3N2. The present case indicates the potential development of encephalopathy in adults under certain conditions.

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