Veille documentaire MTPH

Auteur     Anita Riipinen
Auteur     Markku Sallmén
Auteur     Lea Hedman
Auteur     Anneli Ojajärvi
Auteur     Marja-Liisa Lindbohm
Auteur     Mira Meriluoto
Auteur     Heljä-Marja Surcel
Auteur     Helena Taskinen
Auteur     Mika Nuutila
Auteur     Riitta Karikoski
Auteur     Klaus Hedman
Auteur     Maria Söderlund-Venermo
Volume     71
Numéro     12
Pages     836-841
Publication     Occupational and Environmental Medicine
ISSN     1470-7926
Date     Dec 2014
Résumé     BACKGROUND: Human parvovirus B19 (B19V) infection during early pregnancy increases the risk of miscarriage. Studies have inconsistently shown an elevated risk of infection among women with occupational contacts with children. Methodological differences, particularly in defining occupational exposure and in the type of reference group, may explain the conflicting findings. METHODS: This cohort study compared B19V infections in pregnant day-care employees and healthcare professionals during a B19V epidemic in Finland. Women were identified from the files of nationwide trade unions and the National Supervisory Authority for Welfare and Health. Early-pregnancy maternal B19V IgG was analysed in 3710 women, and infections were defined as seroconversions after analysing in parallel the available umbilical cord blood samples of the 847 seronegative mothers. Independently of the serological status, the actual employment during pregnancy was assessed using registered information on employment history. RESULTS: B19V infections were more common among day-care employees (22/331, 6.6%), than among those working in healthcare (12/326, 3.7%). The adjusted HRs of B19V infection, using proportional hazard regression, was 2.63 (95% CI 1.27 to 5.46) among all women and 5.59 (95% CI 1.40 to 22.4) among nulliparous women. CONCLUSIONS: Day-care employees are at an increased risk of B19V infection, which warrants preventive measures.