Congenital anomalies in the offspring of nurses: association with area of employment during pregnancy
Auteur Helen Dimich-Ward
Auteur D Le Nhu
Auteur Kris Beking
Auteur Anne Dybuncio
Auteur John J Spinelli
Auteur Richard P Gallagher
Auteur Pamela A Ratner
Auteur Laura Arbour
Auteur Kay Teschke
Résumé The purpose of this study was to determine whether registered nurses in specific areas of employment during pregnancy had a higher risk for congenital anomalies in their offspring. An offspring cohort (n = 22,611) was created through linkage of the British Columbia Vital Statistics Agency live and stillbirth records from 1986 to 2000, to a female cohort database of registered nurses. Of these, 16,005 (70.8%) were registered in a specific area of employment when pregnant. Odds ratios were calculated using generalized estimating equations (GEE), binary logistic regression with adjustment for sex, mother’s age, and year of birth. Elevated risks of congenital anomalies were found for the singleton offspring of nurses employed in the following areas: operating rooms and pediatric nursing units (heart anomalies); maternal newborn units (integument); emergency room (respiratory system); and psychiatry (upper alimentary tract). Further research is needed to determine whether these are chance or consistent findings and whether exposure patterns might provide biological plausibility.
Publication International Journal of Occupational and Environmental Health
Volume 17
Numéro 3
Pages 195-201
Date 2011 Jul-Sep
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