Mumps outbreak in a highly vaccinated student population, The Netherlands, 2004

Publié le 05 juillet 2010 • Catégorie(s) : Risques biologiques, Vaccination •

Auteur Heinrich J Brockhoff
Auteur Liesbeth Mollema
Auteur Gerard J B Sonder
Auteur Cees A Postema
Auteur Robert S van Binnendijk
Auteur Robert H G Kohl
Auteur Hester E de Melker
Auteur Susan J M Hahné
Résumé In September 2004 a mumps outbreak occurred at an international hotel school in The Netherlands. We investigated this outbreak to identify risk factors for mumps. There were 105 mumps cases (overall mumps attack rate (AR) 12% (95% CI: 10-15%)). The AR for Dutch vaccinated and unvaccinated participants was 12% (95% CI: 10-15%) and 15% (95% CI: 3-42%), respectively. Independent risk factor was mumps contact. Explanations for the relatively high AR among vaccinated participants include primary vaccine failure, waning immunity and incomplete vaccine-induced immunity in the context of high mumps virus exposure in a school party and a crowded boarding school.
Publication Vaccine
Volume 28
Numéro 17
Pages 2932-2936
Date Apr 9, 2010