Focus on fresh frozen plasma – facilitating optimal management of bleeding through collaboration between clinicians and transfusion specialists on component specifications

MacLennan, Sheila

doi:10.1016/j.lpm.2016.06.021

Focus on fresh frozen plasma – facilitating optimal management of bleeding through collaboration between clinicians and transfusion specialists on component specifications

Affiliations : ¹NHSBT Leeds Centre Bridle Path Leeds LS15 7TW UK

Date 2016 Juillet, Vol 45, Num 7-8, Part 2, pp e299-e302Revue : La Presse médicaleDOI : 10.1016/j.lpm.2016.06.021

Quarterly Medical Review

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SummaryBackgroundA symposium on plasma for direct clinical use was held in September 2015 by the European directorate for the quality of medicines and healthcare (EDQM) in order to consider changes to the Council of Europe guide to the preparation, use and quality assurance of blood components monographs on plasma components.MethodsThe programme reviewed use of plasma in various settings, novel components, adverse reactions, manufacturing and quality monitoring issues.ResultsThe main requirement identified was that plasma should be made available to support early transfusion in the trauma/massive haemorrhage setting. Further guidance on component manufacturing and reviewing of quality monitoring requirements will also be addressed.ConclusionA working group has been established to review component monographs and other advice in the guide relating to plasma components, with the aim of providing optimal components to support clinical management of patients requiring plasma.

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Source : Elsevier-Masson

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MacLennan S. Focus on fresh frozen plasma – facilitating optimal management of bleeding through collaboration between clinicians and transfusion specialists on component specifications. La Presse médicale. 2016 Jui;45(7-8):e299-e302.