central tolerance

Preferred Label : central tolerance;

MeSH definition : The mechanism, in central lymphoid organs (THYMUS; BONE MARROW), that prevents immature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished by CLONAL ANERGY and CLONAL DELETION.;

MeSH synonym : tolerance, central;

Wikipedia link : https://en.wikipedia.org/wiki/Central tolerance;

Details

Origin ID

D061167;

UMLS CUI

C3179074;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Record concept(s)
- central tolerance [MeSH concept]
Semantic type(s)
- Organ or Tissue Function [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

All resources
or only the major
or use the search engine

recommendations
documents concerning education
documents for patients