fms-like tyrosine kinase 3

Preferred Label : fms-like tyrosine kinase 3;

MeSH definition : A receptor tyrosine kinase that is involved in HEMATOPOIESIS. It is closely related to FMS PROTO-ONCOGENE PROTEIN and is commonly mutated in acute MYELOID LEUKEMIA.;

MeSH synonym : antigens, cd135; cd135 antigen; fetal liver kinase-3; stem cell tyrosine kinase 1; antigen, cd135; fetal liver kinase-2; fetal liver kinase 2; fetal liver kinase 3; cd135 antigens; fms like tyrosine kinase 3;

CISMeF synonym : EC 2.7.1.112;

Registry Number MeSH : EC 2.7.10.1;

Is substance : O;

UNII : EC 2.7.10.1;

Details

Origin ID

D051941;

UMLS CUI

C0287186;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene [MeSH Supplementary Concept]
- 15-(2-(pyrrolidin-1-yl)ethoxy)-7,12,25-trioxa-19,21,24-triazatetracyclo(18.3.1.1(2,5).1(14,18))hexacosa-1(24),2,4,9,14(26),15,17,20,22-nonaene [MeSH Supplementary Concept]
- N1-(3-(4-(((5-(tert-butyl)-3-isoxazolyl)aminocarbonyl)amino)methylphenyl)-1H-5-pyrazolyl)-4-(2-morpholinoethoxy)benzamide [MeSH Supplementary Concept]
- gilteritinib [MeSH Supplementary Concept]
Record concept(s)
- fms-Like tyrosine kinase 3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- FLT3 protein, human [MeSH Supplementary Concept]
- FLT3 protein, rat [MeSH Supplementary Concept]
- Flt3 protein, mouse [MeSH Supplementary Concept]
- TRIP11-FLT3 fusion protein, human [MeSH Supplementary Concept]
- flt3 protein, zebrafish [MeSH Supplementary Concept]
See also
- Immunoglobulin Domains [MeSH Descriptor]
See also (suggested by CISMeF)
- quizartinib [MeSH Supplementary Concept]
See also inter- (CISMeF)
- acute myeloid leukemia with FLT3 mutation [Indication]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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