MeSH definition : Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other
position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic
degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include
ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic
and cytotoxic properties.;
Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other
position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic
degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include
ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic
and cytotoxic properties.