Preferred Label : receptors, tie;
MeSH definition : A family of structurally-related tyrosine kinase receptors that are expressed predominantly
in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION,
PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain
Ig and EGF domains.;
MeSH synonym : tie receptor family; tie receptor tyrosine kinase; tie receptors; tie receptor tyrosine kinases; receptor tyrosine kinase tie; family, tie receptor; receptor family, tie; TIE Receptor; Receptor, TIE;
CISMeF synonym : EC 2.7.1.112;
Registry Number MeSH : EC 2.7.10.1;
MeSH annotation : GEN; prefer specifics; general or unspecified; prefer specifics;
Is substance : O;
UNII : EC 2.7.10.1;
Origin ID : D042764;
UMLS CUI : C0210527;
Allowable qualifiers
Record concept(s)
Semantic type(s)
A family of structurally-related tyrosine kinase receptors that are expressed predominantly
in ENDOTHELIAL CELLS and are essential for development of BLOOD VESSELS (NEOVASCULARIZATION,
PHYSIOLOGIC). The name derives from the fact that they are tyrosine kinases that contain
Ig and EGF domains.