Preferred Label : photobleaching;
MeSH definition : Light-induced change in a chromophore, resulting in the loss of its absorption of
light of a particular wave length. The photon energy causes a conformational change
in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in
the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents
problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On
the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY
AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS
in the CELL MEMBRANE.;
Wikipedia link : https://en.wikipedia.org/wiki/Photobleaching;
Origin ID : D038761;
UMLS CUI : C1138417;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
Light-induced change in a chromophore, resulting in the loss of its absorption of
light of a particular wave length. The photon energy causes a conformational change
in the photoreceptor proteins affecting PHOTOTRANSDUCTION. This occurs naturally in
the retina (ADAPTATION, OCULAR) on long exposure to bright light. Photobleaching presents
problems when occurring in PHOTODYNAMIC THERAPY, and in FLUORESCENCE MICROSCOPY. On
the other hand, this phenomenon is exploited in the technique, FLUORESCENCE RECOVERY
AFTER PHOTOBLEACHING, allowing measurement of the movements of proteins and LIPIDS
in the CELL MEMBRANE.
