Preferred Label : receptor, epha1;
MeSH definition : The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing
human hepatocellular carcinoma cell line and is highly conserved among many mammalian
species. Overproduction of the EphA1 receptor is associated with tumors and tumor
cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and
KIDNEY; which is in contrast to many other members of the Eph receptor that are found
primarily in tissues of the nervous system.;
MeSH synonym : epha1 protein; epha1 receptor; epha1 receptor tyrosine kinase; eph receptor;
CISMeF synonym : EC 2.7.1.112;
Registry Number MeSH : EC 2.7.10.1;
Is substance : O;
UNII : EC 2.7.10.1;
Origin ID : D036082;
UMLS CUI : C0916831;
Allowable qualifiers
Record concept(s)
Semantic type(s)
The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing
human hepatocellular carcinoma cell line and is highly conserved among many mammalian
species. Overproduction of the EphA1 receptor is associated with tumors and tumor
cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and
KIDNEY; which is in contrast to many other members of the Eph receptor that are found
primarily in tissues of the nervous system.