Hydroxymethylglutaryl-CoA reductases, NAD-Dependent

Preferred Label : Hydroxymethylglutaryl-CoA reductases, NAD-Dependent;

MeSH definition : Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.;

MeSH synonym : coa-reductase, nad-dependent 3-hydroxy-3-methylglutaryl; hmg coa reductase, nad-dependent; hmg coa reductases, nad dependent; hydroxymethylglutaryl coa reductase, nad-dependent; nad-dependent hydroxymethylglutaryl-coa reductases; hmg coa reductases, nad-dependent; 3-hydroxy-3-methylglutaryl coa-reductase, nad-dependent; nad-dependent 3-hydroxy-3-methylglutaryl coa-reductase; hmg coa reductase, nad dependent; hydroxymethylglutaryl coa reductase, nad dependent;

Registry Number MeSH : EC 1.1.1.88;

MeSH annotation : do not confuse with HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT;

Is substance : O;

UNII : EC 1.1.1.88;

Details

Origin ID

D025781;

UMLS CUI

C0949721;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
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- blood [MeSH Qualifier]
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Record concept(s)
- Hydroxymethylglutaryl-CoA reductases, NAD-Dependent [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

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