Preferred Label : nuclease protection assays;
MeSH definition : Techniques for measuring specific nucleic acid interaction with another nucleic acid
or with a protein by digestion of the non-interacting nucleic acid by various nucleases.
After all non-interacting regions are eliminated by nuclease digestion, the protected
nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to
analyze the DNA contact sites of DNA-BINDING PROTEINS.;
MeSH synonym : assay, nuclease protection; assays, nuclease protection; nuclease protection assay;
Origin ID : D023282;
UMLS CUI : C0887951;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
Techniques for measuring specific nucleic acid interaction with another nucleic acid
or with a protein by digestion of the non-interacting nucleic acid by various nucleases.
After all non-interacting regions are eliminated by nuclease digestion, the protected
nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to
analyze the DNA contact sites of DNA-BINDING PROTEINS.
