Preferred Label : spectrometry, mass, electrospray ionization;
MeSH definition : A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins
and macromolecules. The technique involves preparing electrically charged droplets
from analyte molecules dissolved in solvent. The electrically charged droplets enter
a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the
droplet size, thereby increasing the coulombic repulsion within the droplet. As the
charged droplets get smaller, the excess charge within them causes them to disintegrate
and release analyte molecules. The volatilized analyte molecules are then analyzed
by mass spectrometry.;
MeSH synonym : electrospray ionization mass spectrometry; esi mass spectrometry; mass spectrometry, esi; spectrometry, esi mass;
Wikipedia link : https://en.wikipedia.org/wiki/Spectrometry, mass, electrospray ionization;
Origin ID : D021241;
UMLS CUI : C0596495;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins
and macromolecules. The technique involves preparing electrically charged droplets
from analyte molecules dissolved in solvent. The electrically charged droplets enter
a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the
droplet size, thereby increasing the coulombic repulsion within the droplet. As the
charged droplets get smaller, the excess charge within them causes them to disintegrate
and release analyte molecules. The volatilized analyte molecules are then analyzed
by mass spectrometry.
