MeSH definition : A method for ordering genetic loci along CHROMOSOMES. The method involves fusing irradiated
donor cells with host cells from another species. Following cell fusion, fragments
of DNA from the irradiated cells become integrated into the chromosomes of the host
cells. Molecular probing of DNA obtained from the fused cells is used to determine
if two or more genetic loci are located within the same fragment of donor cell DNA.;
A method for ordering genetic loci along CHROMOSOMES. The method involves fusing irradiated
donor cells with host cells from another species. Following cell fusion, fragments
of DNA from the irradiated cells become integrated into the chromosomes of the host
cells. Molecular probing of DNA obtained from the fused cells is used to determine
if two or more genetic loci are located within the same fragment of donor cell DNA.