Preferred Label : hl-60 cells;
MeSH definition : A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA.
HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors
for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity
and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture
Collection, 7th ed, pp127-8);
MeSH synonym : cell, hl60; hl-60 cell; hl60 cells; cells, hl60; hl60 cell; HL 60 cells;
MeSH annotation : almost always NIM with no subheadings; check HUMAN; do not routinely add LEUKEMIA,
PROMYELOCYTIC, ACUTE;
Origin ID : D018922;
UMLS CUI : C0282549;
Allowable qualifiers
Record concept(s)
Semantic type(s)
- Cell [UMLS semantic type]
A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA.
HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors
for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity
and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture
Collection, 7th ed, pp127-8)