spheroids, cellular

Preferred Label : spheroids, cellular;

MeSH definition : Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. The ability to form spheroids is a characteristic trait of CULTURED TUMOR CELLS derived from solid TUMORS. Cells from normal tissues can also form spheroids. They represent an in-vitro model for studies of the biology of both normal and malignant cells. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4);

MeSH synonym : cellular spheroid; cellular spheroids; multicellular spheroid; multicellular spheroids; spheroid, cellular; spheroid, multicellular; spheroids, multicellular;

MeSH annotation : do not confuse with spheroid bodies referring to axons in neuropathol; if tumor spheroids coordinate with TUMOR CELLS, CULTURED;

Details

Origin ID

D018874;

UMLS CUI

C0282501;

Allowable qualifiers
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- cytology [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- enzymology [MeSH Qualifier]
- immunology [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- microbiology [MeSH Qualifier]
- parasitology [MeSH Qualifier]
- pathology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- transplantation [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- virology [MeSH Qualifier]
Record concept(s)
- spheroids, cellular [MeSH concept]
Semantic type(s)
- Cell [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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