Preferred Label : Patch-Clamp techniques;
MeSH definition : An electrophysiologic technique for studying cells, cell membranes, and occasionally
isolated organelles. All patch-clamp methods rely on a very high-resistance seal between
a micropipette and a membrane; the seal is usually attained by gentle suction. The
four most common variants include on-cell patch, inside-out patch, outside-out patch,
and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that
is control the voltage across the membrane and measure current flow, but current-clamp
methods, in which the current is controlled and the voltage is measured, are also
used.;
MeSH synonym : technics, patch-clamp; techniques, patch-clamp; patch-clamp technic; patch-clamp technique; technique, patch-clamp; patch-clamp technics; patch clamp technics; technic, patch-clamp; patch clamp techniques; Patch Clamp Technique; Clamp Technique, Patch; Clamp Techniques, Patch; Technique, Patch Clamp; Techniques, Patch Clamp; Patch Clamp Technic;
Wikipedia automatic translation : Patch clamp;
MeSH hyponym : Whole-Cell recording; Recording, Whole-Cell; Recordings, Whole-Cell; Whole Cell Recording; Whole-Cell Recordings;
Related MeSH term : Voltage-Clamp techniques; Technique, Voltage-Clamp; Techniques, Voltage-Clamp; Voltage Clamp Techniques; Voltage-Clamp Technique; Voltage-Clamp Technics; Technic, Voltage-Clamp; Technics, Voltage-Clamp; Voltage Clamp Technics; Voltage-Clamp Technic; Voltage Clamp Technique; Voltage Clamp Technic;
MeSH annotation : a cytol technique for removing a tiny patch of plasma membrane; NIM;
Wikipedia link : https://en.wikipedia.org/wiki/Patch clamp;
Origin ID : D018408;
UMLS CUI : C0242625;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
An electrophysiologic technique for studying cells, cell membranes, and occasionally
isolated organelles. All patch-clamp methods rely on a very high-resistance seal between
a micropipette and a membrane; the seal is usually attained by gentle suction. The
four most common variants include on-cell patch, inside-out patch, outside-out patch,
and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that
is control the voltage across the membrane and measure current flow, but current-clamp
methods, in which the current is controlled and the voltage is measured, are also
used.
