Preferred Label : 3t3 cells;
MeSH definition : Cell lines whose original growing procedure consisted being transferred (T) every
3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines
have been developed using several different strains of mice. Tissues are usually fibroblasts
derived from mouse embryos but other types and sources have been developed as well.
The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation
studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.;
MeSH synonym : 3t3 cell; cell, 3t3; cells, 3t3;
MeSH annotation : almost always NIM with no subheadings; check ANIMALS & MICE; do not routinely add
FIBROBLASTS or EMBRYO, MAMMALIAN;
Origin ID : D016475;
UMLS CUI : C0085087;
Allowable qualifiers
- Record concept(s)
- Semantic type(s)
- Cell [UMLS semantic type]
Cell lines whose original growing procedure consisted being transferred (T) every
3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines
have been developed using several different strains of mice. Tissues are usually fibroblasts
derived from mouse embryos but other types and sources have been developed as well.
The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation
studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.
