Preferred Label : giant cells, langhans;
MeSH definition : Multinucleated cells (fused macrophages) seen in granulomatous inflammations such
as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble
foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain
less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern.
Langhans giant cells occur frequently in delayed hypersensitivity.;
MeSH synonym : langhans type giant cells; langhans-type giant cells; cells, langhans-type giant; giant cells, langhans-type; langhans giant cells; cells, langhans giant;
MeSH annotation : a type of macrophage; do not confuse with LANGERHANS CELLS (cutaneous) nor with ISLETS
OF LANGERHANS (pancreatic); A 11 qualif; do not confuse with LANGERHANS CELLS nor with ISLETS OF LANGERHANS;
Wikipedia link : https://en.wikipedia.org/wiki/Giant cells, langhans;
Origin ID : D015744;
UMLS CUI : C0017528;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Record concept(s)
- Semantic type(s)
- Cell [UMLS semantic type]
- UMLS correspondences (same concept)
Multinucleated cells (fused macrophages) seen in granulomatous inflammations such
as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble
foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain
less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern.
Langhans giant cells occur frequently in delayed hypersensitivity.
